Applications for the Developer Tools for Medical Education Public Physiology Research Platform (DTME-PRP) Program Announcement are being solicited by the Assistant Secretary of Defense for Health Affairs, Defense Health Program (DHP). The Developer Tools for Medical Education initiative is primarily focused on the creation of publicly accessible, free, open-license, and/or open-source tools for creation of medical training and education content and technology. The primary, but not exclusive, purposes of this Program Announcement (PA) are to solicit pre-proposals and then by invitation only, request full proposal submissions for research that will: